Micro Scale-Down (MSD)

The Micro Scale-Down (MSD) is a precise rate-freezer and rate-thawer that replicates the stresses of large-scale bio-manufactuing.
This is a small-volume physical model designed to assist freeze-thaw formulation and process design.
Featured in the following papers:
What can the Micro Scale-Down (MSD) do for you?



A scientific breakthrough
Full Method Customization
Custom recipes of up to 16 steps can be set to run automatically with MSD.
Data Export
Export all your data for a deep dive into experiments’ outcomes.
Data Visualization
MSD is prepared for data overview on the go.
Touch Display
Quick and easy to use.
Digital Twin Compatibility
Custom recipes can be translated into Digital Twins and vice-versa.
Specifications
Capacity
1 holder for 6 x 10 mL vials (5 mL of fill volume)
Dimensions (mm)
460 (d) x 360 (w) x 600 (h)
Temperature range
-85 ºC to 25 ºC
Weight (kg)
40
Patent status
Patented

Deciphering protein aggregation in freeze-thaw process: the roles of cold denaturation and shear stress
Co-Authored with: IST-Universidade de Lisboa, Boehringer Ingelheim Pharma