Reduce Development Risk
Test your process virtually before making final decisions. Identify stress points and failures in the process while it’s still cheap to address.
Optimize your processes with our CFD Simulation Services
We work with pharma teams to build validated CFD simulations of freeze-thaw processes.
Our CFD services give you the data needed to make better decisions at every stage of the development and manufacturing process.
Technology Selection & Comparison
Compare freeze-thaw technologies with simulation data before making definitive decisions.
Process Design & Risk Assessment
Map risk, identify failures, and validate your process design.
Scale-Down Model Development
Build scale-down models backed by our validated simulations.
Manufacturing Optimization
Optimize your process through simulation-backed insights.
Scale-Up Preparation
Anticipate your understanding of how your process behaves at manufacturing scale.
Here's what we've simulated before:
What our CFD simulations make possible?
How does it work?
1 - Tell us about your process
Share with us your current challenge, technology, and development stage.
2 - We build your simulation
Our scientists build a validated CFD model for your specific system and use case.
3 - We deliver actionable insights
You receive a simulation analysis with clear, decision-ready outputs.
4 - We deliver actionable insights
Whether you need a quick screening, selecting technology, preparing for scale-up, or need to develop a scale-down model, we’ll deliver the data that makes your decisions more informed.
Why our CFD simulations?
There’s an important difference between simulations that look good on screen and ones that hold up in the lab.
Ours do both!
Deep Cryopreservation Specialization
We specialize in cryopreservation and freeze-thaw science.
Our models are built on domain knowledge accumulated through years of research, published science, and hands-on experimental work.
A Library of Validated Models
We validate our models against real-world data. This grows our library of pre-validated frameworks which we use to move faster than starting from scratch.
Publication-backed
Our methods are published science. The computational approaches and experimental validations behind our CFD simulations have been reviewed and published in scientific journals.
End-to-End Support
We work alongside you and your team through interpretation, decision-making, and implementation.
From Bench to Manufacturing
Our Digital-Twin approach is designed for real-world application. The models we build are created with manufacturing applicability in mind so that the insights you get translate to decisions you can act on in the lab or at scale.
Regulatory-Ready Report
Our deliverables are designed for seamless integration into your regulatory filings. We provide the full technical transparency and data integrity required by regulatory bodies, ensuring your CFD-backed decisions are fully documented, traceable, and ready for audit or filing at a moment’s notice.
Our published results
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Our packs
Screening
A focused, quick-turnaround simulation to test your design or process, without the wait of a full study.
1 Geometry Study
We study 1 geometry of your process or container.
1–2 Simulations
You receive a maximum of 2 simulations.
Brief Report
A clear, concise report summarising what the simulation found.
Results Walkthrough
We walk you through what the results mean for your specific case and what to do next.
Customer Support
Our team is available to help before, during, and after delivery.
Mechanistic Study
An in-depth simulation study examining how your process behaves across multiple conditions and design variables.
Geometry Comparison
Multiple container or equipment geometries simulated side by side so you see exactly how design choices affect outcomes.
Pressure & Shear Field Mapping
Visualize where mechanical stress acts on your product. Critical for protecting sensitive biologics and formulations.
Cryoconcentration Maps
Identify where solute concentration builds up during freezing. This is critical for product stability.
Full Stress-Time Mapping
Understand how stress evolves across the entire process cycle.
Detailed Study Report
A thorough report translating all findings into clear insights. You get to know what was found, what it means, and what to consider next.
Results Walkthrough & Support
We guide your team through the findings and stay available as you apply the results to your process.
Advanced Process
Our most comprehensive offering. It is built around your project's specific needs, from deep optimization to regulatory-ready documentation.
Scope is tailored to your project and agreed before we begin. This service builds on the full Mechanistic Study, extended with the capabilities below:
Parametric Sweep & Optimization
We systematically vary your process parameters to find conditions that deliver the best outcomes, removing guesswork from process design.
Sensitivity Analysis
Identify which parameters matter most and where to focus your quality and control efforts.
Extended Simulation Validation
Rigorous confirmation that the simulation accurately reflects your real process, giving you full confidence in the results.
Risk-Based Interpretation
Findings translated into a structured risk assessment, identifying real threats to product quality and what your process handles safely.
Control Strategy Support
We help define the process controls that manage identified risks, turning simulation insights into actionable, defensible decisions.
Regulatory-Ready Report
A structured, audit-ready report built to support regulatory submissions, tech transfers, or internal approvals.